Stir together mashed avocado, egg, salt, garlic powder, and cayenne pepper until completely combined.
Stir in salmon until mixed well.
Shape into 4 burgers, cover, and refrigerate for at least 20-30 minutes or overnight.
When ready to cook, heat a large skillet over medium-high heat. Add oil to skillet and heat oil. When the oil is hot, add the salmon burgers to a skillet.
Cook until burger releases easily from the skillet and is lightly browned, about 5-7 minutes. Flip and cook until the other side is lightly browned, another 4-6 minutes.
Serve with lime wedges over lettuce or on a whole grain hamburger bun. Enjoy!
Notes
*You can also use 1 (14-ounce) can in place of the 2 (6-ounce) cans.*Optional add-ins: